: This class targets the fungal cell wall rather than the membrane. They inhibit the enzyme -(1,3)-D-glucan synthase. Effect : This blocks the synthesis of
: Azoles inhibit the cytochrome P450-dependent enzyme lanosterol antifungal agent
-(1,3)-D-glucan, a major polysaccharide responsible for maintaining the structural integrity of the cell wall, causing cell lysis. : This class targets the fungal cell wall
: Caspofungin , micafungin, and anidulafungin. 4. Allylamines causing cell lysis. : Caspofungin
: This binding creates physical pores or channels in the membrane. Small essential molecules and cellular organelles leak out of these pores, causing cell death. Common Examples : Amphotericin B, nystatin , and natamycin. 3. Echinocandins