Before a new cancer drug or imaging agent can be tested on humans, it must be proven effective and safe in animal models. Systems like the LI-COR Pearl Trilogy provide the high-quality data required by regulatory bodies (like the FDA) to move a discovery from the lab to the clinic.
The subject is placed in the imaging chamber. PearlCAM software captures the NIR signal and overlays it on a standard grayscale "white light" image for anatomical context. PearlCAM
Because the imaging is non-invasive, researchers can scan the same animal over days or weeks. This reduces the number of animals needed for a study and provides a more accurate timeline of how a tumor grows or shrinks in response to treatment. 🛠 Features and Workflow Before a new cancer drug or imaging agent
Biological tissues naturally glow under certain light; the NIR range used by PearlCAM minimizes this "noise," resulting in much clearer images. PearlCAM software captures the NIR signal and overlays
A fluorescent probe (like IRDye®) is injected into the subject.