Vam_gs.qiao.2.var May 2026

The system sequences through Zernike modes to compensate for aberrations, with optimization processes sometimes completing in minutes, tailored for high-speed scanning (e.g., 133 Hz for ROI).

It achieves cellular resolution across an ultra-large FOV exceeding 50 mm². VAM_GS.Qiao.2.var

Effective imaging up to 900 μm in the mouse brain, crucial for studying deep cortical layers. The system sequences through Zernike modes to compensate

Experiments have shown its capability to study both morphology (structural) and neuronal activity (functional) in mouse brains. 4. Implementation and Data Handling tailored for high-speed scanning (e.g.

It allows for the observation of neural interactions across widely distributed cortical areas, which was previously challenging due to FOV limitations.

It allows researchers to visualize brain structures spanning from superficial layers down to 900 μm depth in a single study.