Athena Heart [310] -

The ATHENA trial was a landmark study that evaluated the efficacy of dronedarone in reducing cardiovascular hospitalizations or death.

: Conduct regular ECGs to monitor for potential proarrhythmic effects or excessive QT prolongation. ATHENA HEART [310]

: Classified as Category X ; it may cause fetal harm and should not be used by pregnant women. Drug Interactions : The ATHENA trial was a landmark study that

: Contraindicated in patients with symptomatic heart failure or recent hospitalization for heart failure (NYHA Class IV or symptomatic Class II-III). ATHENA HEART [310]

: Monitor serum creatinine levels; small increases are common but should be assessed if they persist.

Stop other Class I or III antiarrhythmics (e.g., amiodarone, sotalol) before starting Multaq. Avoid strong (e.g., ketoconazole).